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在模拟环境中训练语言模型用于精神科接诊

Training language models in simulation for psychiatric intake

Samuel Schmidgall · Tim Strother · Alex Bijamov · Min Woo Sun · Anil Palepu · Akshay Goel · et al.

中文摘要

精神科临床接诊访谈是主要诊断工具,要求临床医生建立融洽关系并厘清复杂重叠的表现。本研究表明,在模拟环境中进行多轮强化学习(RL)可提升语言模型在结构化文本精神科接诊中的表现,涵盖病史采集、鉴别诊断和初始管理计划。在一项随机双盲交叉研究中(N=60对匹配场景,120次接诊),将RL训练的智能体与相同提示的基础模型进行比较,32名委员会认证的精神科医生角色扮演标准化患者,由15名独立委员会认证的精神科医生对去标识化转录进行评分。训练后的智能体在76.7%的匹配场景对中优于基础模型(p<0.0001),在改编的临床检查评分表(d_z=0.77,p<0.0001)、以患者为中心的沟通(82.0% vs. 65.2%,p<0.001)和鉴别诊断适当性(68.3% vs. 33.3%,p<0.001)上均有提升。在127个经精神科医生验证的模拟接诊场景中,训练后的智能体临床评分表得分几乎翻倍(0.706 vs. 0.379;复合奖励0.564 vs. 0.294,p<0.0001)。为系统探究对话安全性,我们建立了两个德尔菲共识分类法,分别针对临床安全风险和关系能力,并据此衍生出256个具有挑战性的对抗性表现;发现模拟环境训练将急性安全风险的漏诊率降低了一半以上(12.9% vs. 30.5%,p<0.0001)。因此,模拟环境为训练和压力测试精神科对话智能体提供了受控测试平台,其收益可迁移至精神科医生扮演的接诊中,但残余差距仍需保障措施和临床医生监督。

关键要点

  1. 01问题:精神科接诊访谈需要复杂技能,语言模型在此场景的表现尚不明确。
  2. 02方法:在模拟环境中使用多轮强化学习训练语言模型,并进行随机双盲交叉研究评估。
  3. 03结果:训练后智能体在76.7%场景中优于基础模型,临床评分表得分几乎翻倍。
  4. 04结果:急性安全风险漏诊率从30.5%降至12.9%,沟通和鉴别诊断适当性显著提升。
  5. 05局限:仍存在残余差距,需要保障措施和临床医生监督。

解读

尚无解读。

原始英文摘要

arXiv:2610.40476v1 Announce Type: new Abstract: In psychiatric practice, the clinical intake interview remains a primary diagnostic instrument, requiring the clinician to establish rapport while disentangling complex, overlapping presentations. Here, we show that multi-turn reinforcement learning (RL) in simulation environments improves language model performance on structured text-based psychiatric intake, spanning history-taking, differential diagnosis, and initial management planning. In a randomized, double-blind crossover study ($N = 60$ matched scenario pairs, 120 encounters) comparing the RL-trained agent against its identically prompted base model, 32 board-certified psychiatrists role-played standardized patients while a separate panel of 15 independent, board-certified psychiatrists scored the de-identified transcripts. The trained agent outperformed the base model in 76.7% of matched scenario pairs ($p < 0.0001$), with gains on an adapted clinical-examination rubric ($d_z = 0.77$, $p < 0.0001$), patient-centered communication (82.0% vs. 65.2%, $p < 0.001$), and differential diagnosis appropriateness (68.3% vs. 33.3%, $p < 0.001$). Across 127 psychiatrist-validated simulated intake scenarios, the trained agent nearly doubled its base model's clinical rubric score (0.706 vs. 0.379; composite reward 0.564 vs. 0.294, $p < 0.0001$). To systematically probe conversational safety, we established two Delphi-consensus taxonomies, of clinical safety risks and relational competencies, from which 256 challenging adversarial presentations were derived; we find that training in simulation environments more than halved under-triage of acute safety risks (12.9% vs. 30.5%, $p < 0.0001$). Simulation environments thus provide a controlled testbed for training and stress-testing psychiatric conversational agents, with gains that transferred to psychiatrist-enacted encounters, though residual gaps require safeguards and clinician oversight.

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